
Join us for one of our Upcoming Academy Webinars!
Sent on: 03-04-2025
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Stroke across scales – impact on blood perfusion and oxygen supply in the brain – a computational perspective
Join us on April 1st at 16:00 CEST (Central European Summer Time) for an exciting talk on cerebral microcirculation and related processes with Franca Schmid, Group Leader at the ARTORG Center for Biomedical Engineering Research at the University of Bern, Switzerland. Microvascular disturbances are common during neurological disorders. These disturbances range from single capillary occlusions (microstroke) to the occlusion of a major feeding artery (ischemic stroke). Assessing the impact of such microvascular alterations experimentally is challenging, which poses a challenge to advancing our understanding of disease origins and treatment. Targeted computational model development is a promising tool to close this gap in knowledge. In the context of microstrokes, we use our bi-phasic blood flow model and our model for microvascular oxygen transport to show that microscale alterations matter for mesoscale blood and oxygen supply. The impact of vascular variability during ischemic stroke is addressed in our unique simulation framework, which directly incorporates structural and functional in vivo data from mouse experiments via inverse modeling. By highlighting the relevance of arterial flow loops during ischemic strokes, we propose that accounting for vascular variability in stroke treatments can be beneficial for stroke outcomes. |
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Wettability Control of Multiphase Flow in Porous Media
Join us on May 6th at 16:00 CEST as Benzhong (Robin) Zhao, an Associate Professor in the Department of Civil Engineering at McMaster University, presents a webinar on the topic of "Wettability Control of Multiphase Flow in Porous Media" The simultaneous flow of multiple fluid phases through porous media is central to a wide range of natural and industrial processes. A key factor influencing such flows is wettability—the tendency of the solid matrix to preferentially attract one fluid over another. Despite decades of research, the complex interplay between wettability and multiphase flow remains an active area of investigation. In this talk, I will present our recent work combining microfluidic experiments and pore-network modeling to uncover the microscale mechanisms and macroscopic implications of wettability control. I will discuss how both homogeneous and heterogeneous wettability conditions influence flow behavior. |