This presentation will provide a summary of Montana State University’s research and development activities leading to successful commercial applications of this technology by providing an overview of our laboratory, field and mathematical modeling efforts, which were collaboratively conducted with the University of Stuttgart and others.  Accompanying work occurred from the single-cell scale to meso-scale reactors, packed sand columns and core samples of up to 70 cm diameter operated at ambient and elevated pressures.  Darcy-, pore network-, and pore-scale re-active transport models have been developed and have guided the experimental and field-scale efforts.